Composition And Function Of Lymph In Humans

Composition And Function Of Lymph In Humans

Edited By Irshad Anwar | Updated on Jul 02, 2025 06:44 PM IST

What Is Lymph?

Lymph is a clear or colourless fluid that flows through the lymphatic system. In essence, the lymphatic system acts as a filter against microbes, organic wastes, toxins, and other types of debris. It carries lymphocytes that move throughout the body fighting infections.

In animals and humans, the extracellular fluid, or the fluid outside the cell, is divided into interstitial fluid, or fluid existing between the tissues, and plasma. It contains small water-soluble substances that flow in between the tissue cells. Plasma and interstitial fluid are similar due to continuous exchange across tissue capillary walls of small solutes, water, and ions.

This Story also Contains
  1. What Is Lymph?
  2. Composition Of Lymph
  3. Other Components of Lymph in Humans
  4. Formation Of Lymph
  5. Proteins And fats
  6. Function Of Lymph
Composition And Function Of Lymph In Humans
Composition And Function Of Lymph In Humans

It does the following functions:

  • The delivery of nutrients to cells.

  • It enables intercellular communication between cells themselves.

  • Interstitial fluid removes metabolic waste products from cells.

The lymphatic system collects the interstitial fluid, and the rest is drained out. The drained fluid moves back to the blood vessels, and the remaining fluid is collected through the lymph capillaries, which are part of the lymphatic capillaries.

Composition Of Lymph

Lymphatic systems are formed by lymph plasma, lymph corpuscles, and lymphoid organs. The composition of the lymph is explained as follows:

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Lymph Plasma

Lymph is interstitial fluid. It has a similar mineral content to plasma. This real antibody contains less calcium than plasma, fewer blood proteins, less phosphorus, and an increased concentration of glucose. Globulin proteins are present in the lymph plasma. Other materials include organic and inorganic substances. It is through the lymph that the exchange between blood and tissue cells takes place in terms of gases and nutrients.

Lymph Corpuscles

These will include leucocytes and amoeboid cells. It contains specialized lymphocytes which take part in inducing immune responses in the human body.

Lymphoid Organs

The lymphatic system comprises many lymph nodes deep within the body. The lymph nodes are linked with lymphatic vessels that circulate the lymph throughout the body. The lymph gets filtered at the lymph nodes. The spleen, tonsils, adenoids, and thymus make up part of the lymphatic system. The spleen is regarded as the largest lymphatic organ in the system and is found under the ribcage, above the stomach, and in the left upper quadrant of the abdomen. Other constituents of the lymphatic system – tonsils, adenoids, and thymus are found on either side of the throat and neck.

Other Components of Lymph in Humans

  • Carbohydrates

  • Lymphocytes

  • Creatinine

  • Water – 94%

  • Urea

  • Chlorides

  • Enzymes

  • Proteins – Albumin, globulin and fibrinogen

  • Non-protein nitrogenous substances

Formation Of Lymph

Lymph is formed from interstitial fluid because the lymph vessel capillaries are permeable. When blood flows through blood capillaries in the tissues, 9/10ths of the fluid from the arterial end flows into the venous end of capillaries. The remaining one-tenth of the fluid then diffuses—in a pressure-driven process—into the very permeable lymph capillaries.

Hence, when lymph flows through lymph capillaries, its composition, including its protein content, is more or less the same as that of the interstitial fluid. Since it is bigger than blood capillaries, proteins present in the interstitial fluid cannot diffuse into blood capillaries. Thus, they enter the lymph vessels which are freely permeable to large particles.

Proteins And fats

More protein and lipid substances are present within tissue fluid from the liver and gastrointestinal tract. Hence, comparatively high amounts of proteins and lipids enter into the lymph vessels of the liver and gastrointestinal tract. As a result, lymph in larger vessels contains more amount of proteins and lipids.

Function Of Lymph

Lymph performs some functions of paramount importance. A few major functions of lymph are mentioned below:

  • It helps to keep the body cells moist.

  • It transports oxygen, hormones, and nutrients to various parts of the body.

  • It carries metabolic waste produced by cells.

  • It carries antibodies and lymphocytes to the blood vessels.

  • The composition of tissue fluid and volume of blood is maintained by it

  • Absorption of fats from the small intestine occurs through lymphatic vessels.

  • Invasion of microbes and foreign substances is not allowed into the lymph nodes.

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Frequently Asked Questions (FAQs)

1. What are the 3 lymphatic organs?

The lymphatic organs include the spleen, thymus, and tonsils. 

2. How do you know if your lymphatic system is blocked?

The symptoms of a blocked lymphatic system include swelling, fatigue, bloating, depression, and excess weight gain.

3. What is the function of the lymphatic system?

The lymphatic system circulates lymph containing white blood cells that fight infections throughout the body.

4. What are the components of the lymphatic system?

The lymphatic system includes all the lymphatic vessels and lymphoid organs including the lymph nodes, thymus, spleen, and lymphatic tissues like Peyer's patches and tonsils.

5. What is the structure and function of lymph nodes?

Lymph nodes are small, bean-shaped organs that extend the immune system by filtering the viruses, bacteria, and other causative agents of disease that circulate through the lymphatic system.

6. What are the main components of lymph?
Lymph consists primarily of water, along with dissolved substances such as proteins, lipids, glucose, electrolytes, and cellular debris. It also contains white blood cells, particularly lymphocytes, which are crucial for immune function. Unlike blood, lymph does not contain red blood cells or platelets.
7. How does the composition of lymph change with age?
The composition of lymph can change with age in several ways:
8. How does lymph composition differ in various parts of the body?
Lymph composition can vary depending on its location in the body:
9. What is the role of lymph in the transport of hormones?
Lymph plays a role in hormone transport, although it's generally less significant than blood:
10. How is lymph formed in the human body?
Lymph is formed when excess interstitial fluid (fluid between cells) is collected by tiny lymph capillaries. This occurs when blood plasma leaks out of blood capillaries due to hydrostatic pressure, and not all of it is reabsorbed. The excess fluid, along with proteins and other substances, enters the lymphatic system as lymph.
11. How does exercise affect lymph flow and composition?
Exercise has several effects on lymph flow and composition:
12. How does the lymph system interact with the cardiovascular system?
The lymphatic system and cardiovascular system are closely interconnected:
13. How does the lymphatic system contribute to fluid homeostasis?
The lymphatic system contributes to fluid homeostasis in several ways:
14. What is the significance of the thoracic duct in lymph circulation?
The thoracic duct is the largest lymphatic vessel in the body and plays a crucial role in lymph circulation:
15. What is the primary function of lymph in the human body?
The primary function of lymph is to maintain fluid balance in tissues by collecting excess interstitial fluid and returning it to the bloodstream. Additionally, lymph plays a crucial role in the immune system by transporting white blood cells and antibodies throughout the body, and helps in the absorption of fats from the digestive system.
16. How does lymph contribute to the body's immune response?
Lymph contributes to the immune response by transporting pathogens, antigens, and cellular debris to lymph nodes, where they encounter immune cells. This triggers an immune response, leading to the production of antibodies and activation of lymphocytes. Lymph also carries these immune cells and antibodies back into circulation, allowing them to fight infections throughout the body.
17. What is the relationship between lymph and the lymphatic system?
Lymph is the fluid that flows through the lymphatic system. The lymphatic system is a network of vessels, tissues, and organs that collects, transports, and filters lymph. This system works alongside the circulatory system to maintain fluid balance and support immune function.
18. How does lymph move through the body?
Unlike blood, which is pumped by the heart, lymph moves through the body via a combination of mechanisms:
19. What role does lymph play in fat absorption?
Lymph plays a crucial role in fat absorption from the digestive system. In the small intestine, dietary fats are broken down and packaged into small droplets called chylomicrons. These chylomicrons are too large to enter blood capillaries directly, so they are absorbed by specialized lymph vessels called lacteals. The lymph carrying these fats, known as chyle, appears milky and is transported through the lymphatic system before being released into the bloodstream.
20. How does the pH of lymph compare to that of blood?
The pH of lymph is generally similar to that of blood, typically ranging between 7.35-7.45. However, lymph pH can vary slightly depending on its location in the body and the metabolic activities of surrounding tissues. The buffering capacity of lymph is lower than that of blood, making it more susceptible to pH changes in response to local conditions.
21. What are lymphocytes, and why are they important components of lymph?
Lymphocytes are a type of white blood cell crucial for the immune system. They are important components of lymph because:
22. How does the oxygen content of lymph compare to that of arterial and venous blood?
The oxygen content of lymph is generally lower than both arterial and venous blood. This is because:
23. How does the composition of lymph change during an infection?
During an infection, the composition of lymph changes in several ways:
24. What is the relationship between lymph and cerebrospinal fluid?
While lymph and cerebrospinal fluid (CSF) are both clear fluids involved in maintaining the body's internal environment, they have distinct roles and compositions:
25. How does the protein content of lymph compare to that of blood plasma?
The protein content of lymph is generally lower than that of blood plasma. This is because:
26. Why does lymph appear clear or slightly yellowish?
Lymph appears clear or slightly yellowish because it lacks red blood cells, which give blood its characteristic red color. The yellowish tint, when present, is due to the presence of fats and proteins in the fluid.
27. How does the composition of lymph change as it moves through the lymphatic system?
As lymph moves through the lymphatic system, its composition changes:
28. What is the role of lymph in maintaining osmotic balance?
Lymph plays a crucial role in maintaining osmotic balance by:
29. What happens if lymph flow is obstructed or impaired?
If lymph flow is obstructed or impaired, it can lead to a condition called lymphedema. This results in:
30. What is lymph and how does it differ from blood?
Lymph is a clear, colorless fluid that circulates in the lymphatic system. Unlike blood, which contains red blood cells and flows in a closed circulatory system, lymph is derived from interstitial fluid and flows in an open system. Lymph helps remove waste products and excess fluid from tissues, and plays a crucial role in the immune system.
31. How does the lymphatic system interact with the immune system in mucosal tissues?
The lymphatic system and immune system interact closely in mucosal tissues:
32. What is the significance of lymph in the spread of certain diseases?
Lymph can play a significant role in the spread of certain diseases:
33. What is the relationship between lymph and inflammation?
Lymph and inflammation are closely related:
34. What is the significance of lymph in the body's detoxification processes?
Lymph plays a significant role in the body's detoxification processes:
35. What is the significance of lymph nodes in relation to lymph function?
Lymph nodes are small, bean-shaped structures located along lymphatic vessels. They play a crucial role in:
36. What role does lymph play in the body's defense against cancer?
Lymph plays several important roles in the body's defense against cancer:
37. How does the lymphatic system contribute to lipid metabolism?
The lymphatic system plays a crucial role in lipid metabolism:
38. What is the role of lymph in wound healing?
Lymph plays several important roles in wound healing:

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