Biomolecules

Biomolecules

Irshad AnwarUpdated on 04 Oct 2025, 03:43 PM IST

Biomolecules are the basic organic molecules found in the human body. Biomolecules NEET Notes are important for NEET Biology preparation and class 11 Biology Notes. They include carbohydrates, proteins, lipids, nucleic acids, vitamins, and minerals. The function of biomolecules involves providing energy, building structure and storing genetic information. Understanding the types of biomolecules and the functions of biomolecules is key to scoring on the NEET exam.

This Story also Contains

  1. Types of Biomolecules
  2. Functions of Biomolecules NEET Biology
  3. Metabolism: Anabolism vs Catabolism in Biomolecules
  4. Role of Biomolecules in Health
  5. Biomolecules in Health and Disease - NEET Notes
  6. Enzymes and Biomolecules
  7. Biomolecules NEET MCQs (With Answers & Explanations)
  8. Recommended Video on Biomolecules
Biomolecules
Biomolecules

Biomolecules are classified into macromolecules and micromolecules. Macromolecules include proteins, nucleic acids, and polysaccharides. Micromolecules include vitamins, minerals and water. Macromolecules are polymers built from repeating units. Like amino acids form proteins, nucleotides form nucleic acids, and monosaccharides form polysaccharides. The functions of biomolecules include energy storage, catalysis, heredity and cell communication. For NEET aspirants, mastering these concepts through NEET Biology Notes and practising NEET MCQs ensures a strong foundation in Class 11 Biology Notes.

Types of Biomolecules

Biomolecules are needed by the body to perform different life processes. The types of biomolecules include proteins, carbohydrates, lipids, nucleic acids, vitamins, and minerals. Carbohydrates and lipids are available for energy production and storage, while nucleic acids( DNA and RNA) carry genetic material. For exams, the functions of biomolecules are a key focus area. The various types of biomolecules are listed below:

Carbohydrates: Types and Functions

Carbohydrates are organic molecules made of carbon, hydrogen, and oxygen in a 2:1 ratio. They may be simple sugars or complex polysaccharides.

  • Simple carbohydrates: glucose, a quick energy source

  • Complex carbohydrates: starch, cellulose, long‑term energy and structure

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Carbohydrates are responsible for providing energy and also help in building the cell walls of the cell. They are crucial in NEET Biology Notes and often appear in NEET MCQs.

Types of Carbohydrates

Different types of carbohydrates are discussed below:

Type

Sugar Units

Examples

Description

Monosaccharides

1 unit

Glucose


  • Simple sugar

  • Basic unit of carbohydrates.

Disaccharides

2 units

Sucrose (Glucose + Fructose)


  • Formed by linking two monosaccharides.

Oligosaccharides

2–10 units

Raffinose


  • Contains a few monosaccharide units

  • Not as large as polysaccharides.

Polysaccharides

More than 10 units

Starch, Cellulose


  • Large, complex carbohydrates are made of many monosaccharide units.

Functions of Carbohydrates

Some of the major functions of carbohydrates are discussed below in the table:

Function

Description

Primary Source of Energy

Provides quick energy through glucose for body and brain functions.

Energy Storage

Excess glucose is stored as glycogen in the liver and muscles for later use.

Sparing Protein Use

Prevents proteins from being used for energy, preserving them for body repair.

Fat Metabolism

Helps in the complete oxidation of fats and prevents ketone body formation.

Structural Role

Forms part of DNA (deoxyribose) and RNA (ribose), essential for the genetic code.

Proteins: Types and Roles

Proteins are large biomoleculesmade of amino acids. Amino acids join by peptide bonds to form complex structures. Proteins are essential in NEET Biology Notes and Class 11 Biology Notes because they perform multiple roles in the body.

Proteins build body structure and speed up the reactions taking place in different processes. They act as catalysts and are responsible for determining the shape of how they work. Sometimes they also work as enzymes. Protein is also known as an amino acid polymer because it is made up of organic compounds. There are 20 types of amino acids, each contributing to protein diversity.

Types of Proteins

Some major types of protein and their structure and composition are discussed below:

Type

Structure/Composition

Examples

Description

Simple Proteins

Made of only amino acids

Albumin, Globulin


  • Yield only amino acids on hydrolysis

  • no non-protein part.

Conjugated Proteins

Protein + non-protein part

Hemoglobin (protein + heme group)


  • Contain a prosthetic group like metal ions, lipids, or carbohydrates.

Fibrous Proteins

Long, thread-like structure

Keratin, Collagen


  • Provide structural support

  • insoluble in water.

Globular Proteins

Spherical, compact structure

Enzymes, Antibodies


  • Functional proteins

  • Soluble in water and performs metabolic functions.

Derived Proteins

Formed from the breakdown of proteins

Peptones, Proteoses


  • Products of partial hydrolysis of simple or conjugated proteins.

Functions of Protein

Protein is involved in enzymatic activities, as hormones, in the structure and shape of the cells, and acts in immune defence too. Some major functions are discussed below in the table:

Function

Description

Structural Support

Proteins like collagen and keratin provide strength and structure to tissues.

Enzymatic Activity

Enzymes (which are proteins) catalyse biochemical reactions in the body.

Transport

Proteins like haemoglobin transport oxygen and others help carry nutrients.

Defense Mechanism

Antibodies (immunoglobulins) are proteins that help fight infections.

Hormonal Regulation

Some hormones, like insulin and glucagon, are proteins that regulate metabolism.

Lipids: Types and Functions

Lipids are compounds soluble in nonpolar solvents and contain a large number of carbon-hydrogen atoms. Lipids are responsible for storing fats and oils. It is also important because it is a form of energy storage. It forms the cell membrane of the cell. Lipids are also important for processes like sending signals from one cell to another. They are generally insoluble and can be both saturated and unsaturated fats.

Types of Lipids

Triglycerides act as energy storage or fat, phospholipids are part of cell membranes, and steroids include cholesterol, which is a hormone.

Type

Structure/Composition

Examples

Description

Simple Lipids

Esters of fatty acids with alcohols

Fats (triglycerides), Oils, Waxes

Composed of glycerol and fatty acids,

They serve as energy reserves and insulation.

Compound Lipids

Lipids + additional groups

Phospholipids, Glycolipids

Contain other groups like phosphate or sugar,

Major components of cell membranes.

Derived Lipids

Hydrolysis products of simple/compound lipids

Steroids (cholesterol), Fatty acids

Obtained from the breakdown of simple or compound lipids involved in hormone synthesis.

Steroids

Four fused carbon rings

Cholesterol, Testosterone

Function as hormones, vitamins, and cell membrane components.

Waxes

Esters of long-chain fatty acids & alcohols

Bee wax, Lanolin

Provide protective coatings in plants and animals, water-repellent.

Functions of Lipids

Lipids are involved in energy storage, determination of membrane fluidity plays a role in signal transduction. Some of the major functions of lipids are discussed below:

Function

Description

Energy Storage

Lipids store energy efficiently, providing 9 kcal/g, more than carbohydrates or proteins.

Structural Component

Phospholipids form the basic structure of cell membranes (lipid bilayer).

Insulation and Protection

Lipids insulate the body and protect vital organs by cushioning them.

Hormone Synthesis

Cholesterol is a precursor for steroid hormones like estrogen and testosterone.

Fat-Soluble Vitamin Absorption

Lipids help in the absorption of vitamins A, D, E, and K.

Nucleic Acids: DNA, RNA, and Nucleotides

Nucleic acids are large biomolecules that are made up of a chain of nucleotides. A nucleotide is a molecule that has a sugar, a phosphate group and a nitrogenous base. Nucleic acids are responsible for storing genetic information. DNA and RNA are made up of nucleotides and are two of the best compounds to carry genetic information. DNA carries long-term genetic data, while RNA helps the formation of different types of proteins in the body.

Types of Nucleic Acids

Major types of nucleic acids are discussed below in the table:

Type

Structure/Composition

Examples

Description

DNA (Deoxyribonucleic Acid)

Double-stranded polymer of nucleotides

Human DNA


  • Stores genetic information composed of deoxyribose sugar, phosphate, and bases.

RNA (Ribonucleic Acid)

Single-stranded polymer of nucleotides

mRNA, tRNA, rRNA

Nucleotides

Nitrogenous base + pentose sugar + phosphate

ATP (adenosine triphosphate)


  • Building blocks of nucleic acids

  • ATP stores and transfers energy in cells.

Nucleosides

Nitrogenous base + pentose sugar

Adenosine, Cytidine

Precursors of nucleotides, lacking a phosphate group.

Other Nucleotide Derivatives

Modified nucleotides involved in signalling

cAMP (cyclic AMP), NAD⁺

Important in cellular signalling and metabolic reactions.

Functions of Nucleic Acids

Nucleic acids are involved in the replication of genetic data, and also in the synthesis of proteins, and the transmission of heredity. Some major ones are discussed below in the table:

Function

Description

Genetic Information Storage

DNA stores the hereditary genetic code that controls cell function and inheritance.

Protein Synthesis

RNA helps translate genetic information into proteins via mRNA, tRNA, and rRNA.

Energy Transfer

ATP, a nucleotide, stores and transfers energy within cells for metabolic processes.

Cell Signaling

Molecules like cAMP act as secondary messengers in cellular communication.

Regulation of Metabolism

Nucleotides like NAD⁺ and FAD participate in oxidation-reduction reactions in metabolism.

Types of Vitamins and Coenzymes: Examples and Functions

Vitamins and coenzymes are small organic molecules that assist enzymes in biochemical reactions. They speed up metabolism and regulate essential processes in the body. In NEET Biology Notes and Class 11 Biology Notes, this topic is important because many exam questions focus on the functions of biomolecules and their role in health.

Types of Vitamins and Coenzymes

Some of the major types of vitamins and coenzymes are discussed below:

Type

Structure/Composition

Examples

Description

Fat-Soluble Vitamins

Organic compounds soluble in fats

Vitamins A, D, E, and K

Stored in body fat, involved in vision, bone health, antioxidant functions, and blood clotting.

Water-Soluble Vitamins

Organic compounds soluble in water

Vitamin B-complex, Vitamin C


  • Not stored in large amounts

  • They act mainly as coenzymes in metabolism and antioxidant roles.

Coenzymes

Non-protein organic molecules derived from vitamins

NAD⁺ (from Niacin), FAD (from Riboflavin)


  • Helps enzymes in catalysing biochemical reactions by transferring chemical groups.

Provitamins

Precursors are converted into active vitamins

Beta-carotene (Vitamin A precursor)


  • Converted by the body into active vitamins as needed.

Mineral-based Coenzymes

Inorganic ions that help enzyme function

Zinc, Magnesium


  • Essential for the catalytic activity of some enzymes

  • They act as cofactors alongside coenzymes.

Functions of Vitamins and Coenzymes

Some of the major functions of vitamins and coenzymes are discussed below in the table:

Function

Description

Enzyme Activation

Coenzymes derived from vitamins help enzymes catalyse metabolic reactions efficiently.

Antioxidant Protection

Vitamins like C and E neutralise free radicals, protecting cells from oxidative damage.

Bone and Vision Health

Vitamin D aids calcium absorption for bones.

Vitamin A is essential for vision and eye health.

Immune Function Support

Vitamins like C and A boost immune responses and help fight infections.

Blood Clotting and Healing

Vitamin K is necessary for blood clotting.

B-complex vitamins support wound healing processes.

Examples of Vitamins and Coenzymes

Examples of Vitamins: Vitamin A (retinol), Vitamin C (ascorbic acid), Vitamin D, Vitamin E, Vitamin K, and B-complex vitamins such as B₁ (thiamine), B₂ (riboflavin), B₃ (niacin).

Examples of Coenzymes: NAD⁺ (derived from niacin), FAD (derived from riboflavin), Coenzyme A (derived from pantothenic acid), and TPP (derived from thiamine).

Functions of Biomolecules NEET Biology

Biomolecules NEET Notes explain how biomolecules sustain life. In Class 11 Biology Notes, the functions of biomolecules are a high‑weightage topic and are often asked in NEET MCQs. Biomolecules are of two types.

  • Structural molecules: Proteins, carbohydrates, and lipids provide energy, build tissues, and form membranes.

  • Informational molecules: DNA and RNA store and transmit genetic data. Enzymes, made of proteins, act as catalysts in metabolism. Vitamins and coenzymes regulate enzyme activity and maintain homeostasis.

Understanding the functions of biomolecules like energy storage, catalysis, heredity, and regulation is important. Some important functions of Biomolecules are discussed below:

Function

Explanation

Energy Storage

  • Carbohydrates and lipids are responsible for storing energy for all the processes taking place inside the cell.

  • Carbohydrates are also a form of short-term energy, while lipids are responsible for long-term energy storage.

Structural Support

  • Proteins and carbohydrates are responsible for supporting and maintaining the structure of tissues and cells.

  • Lipids also play a very important role in forming cell membranes due to the presence of phospholipids.

Catalysis

  • Enzymes, such as proteins, act as catalysts to speed up the cellular reactions taking place during different processes, such as digestion and metabolism.

  • For example, in carbohydrate metabolism, an enzyme known as amylase that helps in the breakdown of carbohydrates is a significant function of enzymes in metabolism.

Genetic Information

  • DNA and RNA are responsible for storing nucleic acids, transmitting and then expressing them into genetic information.

  • DNA contains the hereditary material, while ribosomes and RNA transcribe this information to manufacture proteins, thus playing the role of heredity and cell functions.

  • This makes sure that all the traits are packed in the form of protein and are synthesised when needed.

Cell Communication

  • Proteins and lipids are responsible for cell signals and communication between cells.

  • There are certain hormones which are made up of proteins and lipids and help regulate different body processes.

  • The receptors of these hormones are present on the cell membrane where they receive signals.

Regulation and Coordination of Biological Processes


  • These are chemical substances that control and synchronise different functions of the body

  • Most of them are proteins or lipids.

  • Insulin is a protein hormone that regulates glucose concentration in the bloodstream to maintain normal concentration within the body.

Metabolism: Anabolism vs Catabolism in Biomolecules

Metabolism is the sum of all chemical reactions in living organisms. It includes two opposite pathways: anabolism and catabolism. Both pathways work together to support growth, repair, energy supply, and balance in the body. Understanding anabolism vs catabolism in biomolecules is important for exams like NEET Biology and Class 11 Biology Notes. The synthesis and breakdown of biomolecules includes following pathways:

  1. Anabolic Pathways

In anabolism, small and simpler molecules are converted into large and complex molecules, requiring energy input.

Examples: Amino acids from keratin, glucose molecules form glycogen and starch

  1. Catabolic Pathways

In catabolism, large complex molecules are degraded into smaller, simpler molecules.

Examples: Protein is broken down into amino acids, and lipids are broken down into fatty acids

These two pathways are essential for total metabolism in an organism. The difference between the two is given in the table below:

Aspect

Anabolic Pathways

Catabolic Pathways

Definition

Biosynthetic processes that build larger molecules from smaller ones.

Degradative processes that break down large molecules into simpler ones.

Energy Requirement

Requires energy input (endergonic).

Releases energy (exergonic).

Molecules Involved

Builds macromolecules like proteins, nucleic acids, and polysaccharides.

Breaks down macromolecules like carbohydrates, fats, and proteins.

Purpose

Supports growth, repair, and storage.

Provides energy (ATP) for cellular activities.

Example

Synthesis of proteins from amino acids.

Breakdown of glucose in cellular respiration to produce ATP.

Metabolic Pathways Examples

Major examples of Metabolic Pathways are discussed below in the table:

Process

Type

Key Steps

End ProductS

Function

Glycolysis

Catabolic

Breakdown of glucose into pyruvate in the cytoplasm

2 Pyruvate, 2 ATP, 2 NADH

The initial stage of cellular respiration

provides energy and metabolic intermediates.

Krebs Cycle

Catabolic

Oxidation of pyruvate-derived acetyl-CoA in mitochondria

ATP, NADH, FADH₂, CO₂

Generates energy carriers (NADH, FADH₂) for the electron transport chain.

Protein Synthesis

Anabolic

Transcription (DNA → mRNA) and translation (mRNA → protein)

Functional proteins (polypeptides)

Builds proteins necessary for structure, enzymes, and cell function.

Role of Biomolecules in Health

Biomolecules are vital for maintaining human health. They regulate metabolism and support homeostasis in the human body. Biomolecules are involved in the regulation of physiological processes leading to a complex organism’s homeostasis and health condition.

  • Carbohydrates supply quick energy for cellular processes.

  • Proteins build tissues and act as enzymes for reactions.

  • Lipids form cell membranes and store long‑term energy.

  • Nucleic acids store and transmit hereditary information.

Biomolecules in Health and Disease - NEET Notes

Biomolecules are central to human health and disease. They regulate metabolism, maintain homeostasis, and support vital functions. Disorders in biomolecule metabolism, such as diabetes, hypercholesterolemia, and PKU, affect energy balance and overall health. Targeting biomolecules with therapies like insulin, statins, and enzyme replacement is key in modern medicine.

Disorders Related to Biomolecule Metabolism

Some common disorders related to biomolecule metabolism are:

Disorder

Cause

Effect on Metabolism

Health Impact

Diabetes

Lack of insulin (Type 1) or reduced insulin sensitivity (Type 2)

Impaired glucose absorption and utilisation

high blood sugar levels

Leads to fatigue, vision issues, nerve damage, and long-term organ complications

Hypercholesterolemia

High lipid/cholesterol levels due to genetics or poor diet

Excess cholesterol in blood; lipid metabolism imbalance

Risk of atherosclerosis, heart attacks, and strokes

Phenylketonuria (PKU)

Deficiency of the phenylalanine hydroxylase enzyme

Inability to metabolise phenylalanine

Accumulation in the blood

Causes intellectual disability, developmental delays, and neurological disorders if untreated

Biomolecules as Therapeutic Targets

Biomolecules play a central role in the process of finding therapeutic approaches. Strategies that aim at particular biomolecules alter diseases:

  • Insulin therapy for diabetes regulates blood glucose.

  • Statins lower cholesterol in hypercholesterolemia.

  • Enzyme replacement therapy treats PKU by restoring metabolic function.

Advances in biotechnology and pharmacology continue to develop new biomolecular therapies, improving patient outcomes and health management.

Enzymes and Biomolecules

Enzymes are proteins that control the speed of metabolic reactions. They help in both biosynthesis and degradation of biomolecules. Enzymes lower the activation energy and make reactions faster. Catalytic actions of enzymes are involved in biosynthesis as well as the degradation of biomolecules. In NEET Biology Notes and Class 11 Biology Notes, enzymes are often linked with the functions of biomolecules and appear in NEET MCQs.

For example:

  • Specific enzymes of DNA polymerase are used to synthesise DNA

  • Proteases are used to deconstruct proteins into amino acids.

Biomolecules NEET MCQs (With Answers & Explanations)

Important topics in the chapter Biomolecules are the

  • Types of Biomolecules (Proteins, Carbohydrates, Lipids, Nucleic Acids)

  • Functions of Biomolecules

  • Biomolecules in Health and Diseases

  • Enzymes

Practice Questions for NEET

Q1. The cellular pool comprises hundreds of organic and inorganic biomolecules. The organic molecules include

  1. Carbohydrates

  2. Proteins

  3. Nucleic acids

  4. More than one option correct

Correct answer: 4) More than one option correct

Explanation:

The organic molecules present within the cell are categorized into:

1. Carbohydrates:
- Monosaccharides (e.g., glucose) are simple sugars serving as energy sources.
- Polysaccharides (e.g., starch, glycogen) are complex carbohydrates providing both energy and structural support to cells.

2. Proteins:
- Composed of amino acids, proteins are fundamental to various cellular activities such as enzyme function, structural integrity, signal transmission, and material transport.

3. Lipids:
- This group encompasses fats, phospholipids, and steroids which are crucial for energy storage, maintaining cell membrane structure, and participating in signaling pathways.

4. Nucleic Acids:
- DNA and RNA are the genetic material, essential for storing, transferring, and synthesizing proteins according to genetic instructions.

Hence, the correct answer is option 4) More than one option is correct.

Q2. Organic molecules contain

  1. Nitrogen

  2. Sulphur

  3. Oxygen

  4. Zinc

Correct answer: 3) Oxygen

Explanation:

Biomolecules are organic compounds essential to life, composed primarily of carbon (C), hydrogen (H), and oxygen (O). These molecules form the structural and functional basis of living organisms. In addition to these elements, some biomolecules may also contain nitrogen (N), phosphorus (P), sulfur (S), and other trace elements.

Hence, the correct answer is option 3) Oxygen.

Q3. Lecithin, a small molecular weight organic compound found in living tissues, is an example of:

  1. Amino acids

  2. Phospholipids

  3. Glycerides

  4. Carbohydrates

Correct answer: 2) Phospholipids

Explanation:

Some lipids have phosphorus and a phosphorylated organic compound in them. These are phospholipids. They are found in cell membranes. Lecithin is one example.

Option (3) is incorrect, as glycerides are another group of lipids in which both glycerol and fatty acids are present.

Option (1) and (4) are incorrect as amino acids and carbohydrates are separate groups of biomolecules.

Hence, The correct answer is option 2) Phospholipids.

Also Read:

Recommended Video on Biomolecules

Frequently Asked Questions (FAQs)

Q: What are biomolecules in Class 11 Biology?
A:

Biomolecules are organic and inorganic molecules essential for life, including carbohydrates, proteins, lipids, nucleic acids, and enzymes.

Q: What are the types of biomolecules?
A:

The four major types are carbohydrates, proteins, lipids, and nucleic acids.

Q: What is the difference between micromolecules and macromolecules?
A:

Micromolecules are small, simple molecules like amino acids and monosaccharides, while macromolecules are large, complex molecules like proteins, polysaccharides, and DNA.

Q: What is the difference between primary and secondary metabolites?
A:

Primary metabolites are essential for growth (e.g., amino acids, sugars), while secondary metabolites are non‑essential but useful (e.g., alkaloids, pigments).

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