If somebody fails in onemain sub. In 12th and has additional subject also in which he score well then he has to give compartment exam ornot
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According to CBSE examination laws, any student passing in English plus any four other subjects qualify for pass certificate. Normally the 6 subject is opted to open more options or as a cushion subject. In case someone fails in any subject other than English, the sixth subject can replace it.
So, yes if you fail in one subject then that subject won't count and the 6th subject will take its place. But you need to remember that all 5 subjects should be main subjects. And Physical Education won't count.
Also, you will be disqualified for the fail subject. That means, you cannot claim admission in a university for the failed subject if you pass other subjects and pass overall.
Second, you shall still be able to play professional sports and demand sports quota if you fail P.E. It simply does not count.
Hope this helps. Good luck!
But please tell me clearly whether He has to give the compartment exam or not in spite of Being scoring good in 6th additional subject.