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After the woman completed her kidney transplant, the problem of rejection of the transplanted kidney arises. This is because her body will think this new kidney is “foreign” and will try to protect her by “attacking” it. To prevent this rejection, anti-rejection bioactive drugs are administered. These bioactive molecules are called immunosuppressants .

The Anti–rejection (immunosuppressant) medications decrease the body’s natural immune response to a “foreign” substance (your transplanted kidney). They lower (suppress) her immune system and prevent her body from rejecting her new kidney.

The immunosuppressive agent used for preventing rejection of transplanted organs is Cyclosporin-A . It is produced by submerged fermentation of aerobic fungi identified as Trichoderma polysporum .

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