Hello student!

Yes, Human Resources can be pursued with math, No issues in that.

Choosing SP, i.e. Secretarial practice in your 12th/SYJC will not affect your Human resource management course.

Although it would be better to cross-check with the college/university's requirements as well from where you desire to pursue Human Resource Management.

I am hoping this was helpful.

If you have any further queries please feel free to ask.