Hi Krunal,

Yes, you can clear you HSC exams from NIOS. NIOS has sent circular to every State Boards/Universities to instruct their schools and colleges to allow admissions on the basis of Marks Sheets and Certificates issued by NIOS. All schools/Universities have recognized NIOS certificates for admission purpose. It is valid and equivalent to CBSE, ICSE and other State Boards like GSEB. 

All the best!