Correct Answer: Setback

Solution : The correct answer is option 4.

Explanation:

- "Advancement" refers to growth or improvement.

- Let's examine the following alternatives' meanings:

• Refinement is the process of making little adjustments to something in order to make it better or clearer.
• Enhancement: An improvement or increase in the scope, value, or quality.
• Advance - Growth or development.
• A setback is a challenge or issue that prevents you from moving forward as quickly as you would like.