Correct Answer: Pandemic

Solution : The correct choice is the first option .

Explanation :

The term pandemic is a noun that refers to a disease prevalent over an entire country or the whole world. In the context provided, it accurately captures the meaning of a disease that has spread extensively. Pandemic is commonly used in the fields of medicine and public health to describe situations where a disease affects a large geographic area, often crossing international boundaries.

The meanings of the other options are as follows:

• Rustic : It refers to something rural or characteristic of the countryside.
• Panacea : It is a remedy or solution for all difficulties or diseases.
• Epidermis : It is the outer layer of the skin.