Hello aspirant

yes .buy you have  to a qualified a Gate exam or  isro entrance exam with decent rank.after that you hae to attained isro interview .please go through a below given link .you would get a more knowledge about isro eligibility and selection creteria-https://www.google.co.in/url?q=https://engineering.careers360.com/articles/isro-recruitment&sa

Thanku

Yes,
The organization accepts students from state universities. If you have any degrees like BE/BTech/B.Sc. and any other bachelor degree.
The percentage must be more than 65% or above to get selected.
Better to visit the official website of ISRO for more information.
Hope it helps!