It's difficult to say definitively whether your SRM JEE rank of 40498 will guarantee admission to a Biotechnology program at SRM IST. Biotechnology programs are generally competitive, and the cutoff rank varies year by year. While a rank of 40498 might be within the range of potential candidates, it's not a guarantee. Factors like the specific program, seat availability, and the overall performance of other applicants also play a role.

Check cutoff here :

https://engineering.careers360.com/articles/srmjeee-cutoff

With an SRMJEEE rank of 40498, the chances of getting admitted to the B.Tech Biotechnology program at SRM University are likely to be low. However, it's possible, depending on factors like seat availability and the specific cutoff for Biotechnology in the coming counseling process. Careers360 provides information about the expected branch-wise cutoff for SRMJEEE 2025. You can also explore options like specializations within Biotechnology, such as Genetic Engineering.