Yes , there is a significant difference between B.E. and B.tech. the first difference lies in their names only  , B.E. is bachelor of engineering and B.tech is bachelor of technology .We can deduce from their names that B.E. is a theory oriented course and B.tech is technology based or skill oriented course.It lays more focus on practical applications.A B.tech graduate always has an upper hand over one who has done B.E. whether its about placements ,jobs or internships.

Hope you got my point.

Yes, there is some difference between these two branches.

While pursuing B.tech degree, your course will be oriented on skills.

However, B.E courses are data-oriented, that is, they are more theoretical than the former.