Hello Aspirant,

Whether you should go for TIFR Hyderabad, IISc, or IISERs for a PhD in Chemistry depends on multiple aspects, including your interests, faculty expertise, other faculties, facilities, and the career goals you have.

• TIFR Hyderabad is a well-known institute that focuses on advanced research and interdisciplinary research collaborations. It gives students a research-driven environment, which is conducive to focusing and planning for their research agenda. Moreover, TIFR has the research resources that make it a better, exceptional destination because of the access to infrastructure and people.
• IISc Bangalore is the topmost science and engineering institute in India, considering its history, the best of best faculty, one of the best research facilities, and the diversity/exposure. IISc has proven globally that it is one of the best institutes if you would like to consider broad exposure and multiple diverse faculties.
• Even though IISERs (IISER Pune, IISER Kolkata, etc.) are relatively new as institutions, they are growing at a fast pace, focus on science education and research, and they have the research mission that promotes and provides a large number of interdisciplinary relationships that provide a supportive academic culture.

Overall, "better" really depends on what your specific research interests are, who you want to work with, and the type of research responsive culture that best suits you. Ultimately, all three offer great opportunities for a PhD in Chemistry.