Hi Gurcahran,

Habitat destruction is a significant threat to biodiversity, because it can wipe out an entire population of that particular area and then, in turn the ecological chain related to that species and dependent on it.
Habitat destruction can be responsible for death of a large number of species residing in that area, it can eradicate the endemic species, it can result in reduction of gene pool and genetic diversity, in turn production of infertile individuals, inbreeding depression, generation of a completely different species, not suitable for ecosystem etc.,
Finally, the whole global biodiversity can be disturbed.

Feel free to ask doubts in the Comment Section.

I hope this information helps you.

Good Luck!