Hello Lavanya

Of course there is some difference.
In general terms, ISE deals with only software while CSE deals with both software and hardware.
Placement wise both these branches have similar placements, barring a few companies who allow CSE students and not ISE students.

Area of study for computer science

• Deals with both hardware and software components of the computer system
• Covers the core concept of computer science

Area of study for Information Science Engineering (ISE)

• Deals with the study of software like how software development, software testing, and software maintenance happens
• Deals with the application of the computer system

Information Science Engineering Scope

• Managing the automation system of the organisation
• Handling the accounting system of the business and organisation
• Handling the decision support system of the organisation
• Monitoring live projects
• Handling the online system like the online test platform
• Managing the e-commerce, e-business, e-learning and e-governance system

Computer Science Engineering Scope

• Design and development of web application and software application
• Programming and coding
• Managing the IT infrastructure and networking of an organisation
• Software testing
• Website design and development
• Development and management of software tools
• Database administration
• Handling the IT security system of the organisation

Hope it helps you