There are quite a number of posts in UPSC. As you have not mentioned any of it. I am assuming you are asking physical fitness criteria for IAS. So the IAS physical fitness criteria are-

• There is no height, weight and chest girth minimum requirement as such for candidates for the IAS, unlike the technical services. However, if the candidates’ measurements are disproportionate as regarded by the medical board, the candidates can be hospitalized for investigation and chest X-ray can be taken. Please note the technical services have certain minimum requirements.
• Candidates should have a proper vision in the eyes. Corrections permitted are spectacles, CL and refractive surgery like LASIK, ICL, IOL, etc. Those who have myopia with macular degenerative changes will be declared unfit for service in the IAS. People with a squint in the eyes are fit for service. Night blindness is also not a ground for candidates to be declared unfit.
• Blood pressure over 140/90 should be subjected to further testing in the hospital to ascertain whether the abnormal BP is temporary due to excitement, etc. and not an indication of any disease. Only candidates free from any complication of hypertension will be declared fit for service.
• Only candidates free from any complication of diabetes mellitus will be declared fit for service.
• The hearing ability of the candidate should be ‘good’ in each ear and he/she should also be free from any disease of the ear. In case of a defect, the candidate should be subjected to further tests to see if the defect can be remedied by a hearing aid or an operation.
• Pregnant female candidates will be fit except for those services that require physical training. In such cases, the candidates will be declared fit after confinement.
• Candidates’ teeth should be in ‘good order’.
• The heart and lungs of the candidate should be fine.
• There should not be any abdominal disease.
• The feet, hands and limbs are well-formed and there should be no restriction on joint movements.
• There should not be any congenital malformation or defect.
• There should not be any sign of acute or chronic disease indicating an impaired constitution.
• Candidates should bear marks of efficient vaccination.
• The candidates should not have any communicable diseases.
• Candidates with grade I haemorrhoids are declared fit.
• Diseases like hernia, varicose veins, hydrocele, haemorrhoids, etc. are declared temporarily unfit and should be declared fit after successful surgery.
• Candidates with malignancies at the time of entry to service are declared unfit.
• Candidates with transplanted organs are declared unfit. An exception is made only for a corneal transplant.

So there is a chance that for cardiovascular disease, the candidate may not be declared to be fit .

Have a great day!