Hello,

 Indian instute of science education and research (IISER) conduct a exam which is also called SCB channel. SCB stands for "State And Board Channel” . thus eligiblity criteria for this is that candidates should be 

• Passed 10+2 or intermediate examination with science stream 
• Candidates have to secure marks equal or above the cut-off percentage in their respective boards.
• The cut-off percentage marks is 55% in 10+2 level for all boards for SC/ST/KM category candidates.
• There is 5% relaxation in qualifying marks for the OBC-NC & PwD category.

thus if you fulfil there criteria you can give exam 

hope this helps you !

all the best !