Hello,

Yes, you can upload documents from digilocker for your NIOS class 12th.

But few things that you should keep in your mind, if you are applying for NIOS class 12th immediately after finishing class 10th then you won't be eligible to sit for all the subjects in one attempt.

Check following link for more information:

https://school.careers360.com/articles/nios-admission#NIOS-2021-Admission-Eligibility-Criteria

Hope this helps

Thank You