Hello aspirant,

No, it will not create a problem if you are a student with Physics, Chemistry and Biology stream having a improvement marksheet of only one subject. See, whether you're a a regular student or supplementary student, it least matters at the time of the admission. The officials of the conducting board will only check whether you have managed to qualify the minimum eligibility criteria or not. But, yes since you're a supplementary student, so at the time of admission, you have to show your regular marksheet and supplementary marksheet too.

Hope, it helps you.