Cut-off scores are bound to vary each year. But, as per general trends, a score of around 550 is safe in All India quota and around 500 is safe in state quota for an OBC candidate. Since, you haven't mentioned any college, I have given generalized data of colleges all over India. Of you want to know the trends of some particular state, please specify, I can then provide you most accurate data then.

Hii Kartik
If you are applying under 85% state quota seats then you should score above 490 marks and if you are applying under 15% all india quota seats then you should score above 550 marks to secure a seat in government medical college.i hope this information helps you.
Thank you