Yes, you can definitely pursue a nursing course even though you were a commerce student in your +2 (12th grade).

Nursing Courses for Non-Science Students:

• Auxiliary Nursing Midwife (ANM): This is a 2-year diploma program that equips you with the basic knowledge and skills for assisting nurses in patient care.
  
  
• General Nursing Midwifery (GNM): This is a 3-year diploma program that qualifies you to work as a registered nurse in various healthcare settings.
  
  These diploma programs typically require you to have completed your 10+2 (or equivalent) education from a recognized board with a minimum percentage (which can vary depending on the institution). They might not have specific subject requirements from your +2, unlike some other professional courses.
  
  https://www.careers360.com/courses/articles/nursing-course-after-10th-counar
  
  I hope it helps!

Yes Students of all streams Science,Arts,commerce can pursue any nursing course, though Science is preferable. The Indian Nursing Council (INC) has allowed students from Non Science streams to pursue nursing.but before applying to the course You need to do a diploma course for 2 years, called Auxiliary Midwifery Nurse (AMN).to be eligible for the course minimum 40 percent aggregate in English is required for vocational ANM courses from institutes recognized by the Indian Nursing Council.