Yes, you can as there is nothing about the board in the eligibility criteria for the entrance examination. COMEDK is an state level UG entrance examination it means that it accepts all the candidates irrespective of their board of +2. For more details visit careers360 web page on COMEDK. 

hey pranjal!!

yes you can apply for comedk if you have done your 12th from cbse board.

please go through the following link for more details regarding the exam

https://engineering.careers360.com/articles/comedk-uget

if you have any further queries please feel free to ask on our platform

thank you