Hi Bhawna 

Firstly, both the streams are distinct and cannot be compared.

And you can choose a stream of your choice based on your Academic performance, skills , interests and potential.

- in Commerce ,  you have business and management related subjects like Accounts, business studies , economics , maths is optional if you are not so good at maths then you can go for Commerce without maths . 

You can pursue your career in courses like BCom, BBA, CS, CA, LLB or management and business related courses. 

- if you choose non-medical stream, then you should have good numerical and analytical skills. You'll deal with subjects and problems related to chemistry, physics and mathematics.

So if you want to pursue in medical or Engineering field then go for non-medical stream.

Level of study is going to be difficult in class 11, 12 as compared to what you read in class 10. 

So, start thinking about your career , and goals which must be realistic and suits your potential , skills and abilities. 

All The Best!!