Hi, ME is course based master’s degree and it is a academic qualification and it is regarded as more respected and recognised degree. For ME 

candidates must have passed B.E. / B.Tech degree.M.Tech
is two years postgraduate program. The program is basically designed to
equip students with the basic practical skills with sufficient theory
to develop in them the power of systematic thinking and reasoning,
practical approach and exposition and also to understand the principles
involved in the application. Hope this helps you.