Hi Aspirant,

The significant difference between CSE and ISE is that only software is taught in ISE, whereas both software as hardware is taught in CSE.

In terms of Opportunity, almost all companies allow both CSE and ISE students to participate in placements with some exceptions.

But, CSE has a little better scope because it's curriculum is wider than ISE. The only advantage of ISE over CSE is that cutoff for admission is lower for ISE, irrespective of colleges.

I hope this will help you to understand.