Hi there,

There is no such reference book just for first year. There are lots of reference books which have biotechnology topics. You have to check whether the topic you are studying is in the book.  Different books will be having different topics.

Here are some of the Biotechnology books:

Biotechnology by B. D Singh

A Problem Approach by Pranav Kumar & Usha Mina

Gene Cloning and DNA Analysis by T. A. Brown

Principles of Gene Manipulation and Genomics by Sandy B. Primrose, Richard M. Twyman

Biotechnology by lehninger

Igenetivs by peter J Russel

Immunology by Kuby

Just be aware of your topic and the book you should refer to. Hope it helps.

Thank you.