Both courses are good. Opportunities do not lie in a degree it is within the person who has that degree. B. Sc. in Biotechnology is a 3- year undergraduate course, involving an advanced study of the cellular and biomolecular processes for the development of a variety of technologies and products that contribute to improving peoples lives and health. 

Successful graduates of the course are lucratively hired in both private and government sectors, with an initial average annual salary ranging between INR 2.5 and 7 Lacs, depending upon the candidate's expertise in the field. 
Eligibility for B. Sc. in Biotechnology is A minimum aggregate score of 50% (45% for SC/ST candidates) at both Higher Secondary and Senior Secondary (classes X and XII) levels.
Biology, Physics & Chemistry as main subjects at 10+2 level, with a minimum aggregate score of 60%in these three. 
For admission to the course, eligible candidates are needed to qualify a relevant entrance examination, conducted at any of institute, state and national levels.
Some of the major entrance tests conducted in India for admission to the course are : NEST
AIIMS Biotechnology Entrance Test
JNU (Jawaharlal Nehru University) Combined Biotechnology Entrance Examination
CBEEE (Combined Biotechnology Entrance Examination)
DU (University of Delhi) Biotechnology Entrance Examination.
Some of the top institutes offering the course include:
University of Hyderabad-School of Life Sciences, University of Mumbai-Institute of Chemical Technology, National Dairy Research Institute 
Rajiv Gandhi Center for Biotechnology 
Lovely Professional University 
Delhi Technological University-Department of Biotechnology, Indian Institute of Technology-Department of Biochemical Engineering & Biotechnology, Delhi University
Banaras Hindu University
Jawaharlal Nehru University 
Aligarh Muslim University of Mumbai
VIT, BITS, JMI, Christ University.