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Hello Soumadev Bal!
Actually , Coenzymes and metal Ions that are bound very tightly to the enzyme protien are called prosthetic groups ! This is absolute correct statement . This is because coenzymes are of two types - cosubstrates which are loosely bound and prosthetic grup which are tightly bound . A complete catalytic active enzyme with its bound prosthetic group is called holoenzyme . So A is true and B is false.
Hope this will help you!
All the best for your future!.
Thank you!
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