Hey, The cut offs for government medical collaege in Kerala are usually very high especially for sought after colleges like Government Medical College, Trivandrum. 

420-450 will not suffice to get a seat in this college. However, if you reservation (SC/ST) then you may have a chance! 

Hi Paras,

According to last year marks,

State qouta( 2017 marks) -608

SC - 453 

ST - 367.

so it's depend upon which category you are 

For more info 

https://medicine.careers360.com/articles/neet-cutoff-kerala

Thanks