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Photorespiration (also known as the oxidative photosynthetic carbon cycle, or C2 photosynthesis) refers to a process in plant metabolism where the enzyme RuBisCO oxygenates RuBP, causing some of the energy produced by photosynthesis to be wasted.

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Photorespiration is a wasteful pathway that occurs when the Calvin cycle enzyme rubisco acts on oxygen rather than carbon dioxide. Crassulacean acid metabolism (CAM) plants minimize photorespiration and save water by separating these steps in time, between night and day.

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