Hello Syam,

Indian Institute of Science requires Mathematics in 10+2 or equivalent exam from a recognised Board for admission process.

If candidates have Mathematics in their 10+2 or even PCMB students are eligible to apply for Indian Institute of Science.

Candidates who have Computer Science, Biology, Electronics, Statistics, etc in addition to PCM are also eligible to apply.

So if you belong to PCB stream then you are not eligible to apply for Indian Institute of Science.

I hope this helps you.

Good Luck!!