Hello student if you're asking about cleaning entrance examination of. Bsc with Jee Main preparation yes you can but if you're asking to  clear BSc course with Jee main preparation I'm sorry to inform you but it's not possible as Jee main syllabus is  different than BSc syllabus.

To prepare for Jee main syllabus you need to cover the syllabus of. Class 11and 12 of physics chemistry and biology where as in BSc you've different subjects in different semesters.

Feel free to comment if you've any doubt

Good luck