Hey,
Indian Institutes of Science and Research(IISER) admissions are conducted through three channels KVPY,JEE and State Central Boards Channel.
The minimum eligibility criteria is that you should have completed your 12th from Science stream. The candidates can apply through one or all three options but must fulfil the eligibility criteria individually.
For detailed information follow the link given below:
https://engineering.careers360.com/articles/iiser-eligibility-criteria
Hope this helps.
Good luck.

Dear Manish Candidates who have passed 10+2 or equivalent level exam with science stream in 2019 or 2020 are eligible to apply for admissions. Candidates will be admitted to IISER only through following three channels. These channels will be referred to as KVPY, JEE, and SCB, respectively.

All the best 

Hope this helps 

IISER Pune

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