No, You cannot. The eligibility criteria for IISC (KVPY) is 75 Percent aggregate in Maths and Science for general category. If you have failed the eligibility criteria then you cannot get into the college even if you top the exam. Minimum eligibility criteria must be strictly achieved in order to get into a particular institution/ exam. As you have not specified, I think you are from general category. If you are from any reserved category then please specify. Minimum eligibility for SC/ST/PWD is 65 percent aggregate in Maths and science.

The candidate must have passed its 12th with minimum 60%. According to this criteria you are eligible for the exam. Here i am providing you the link which will not only tell you the important points but will also update you about the important dates and all. Kindly go through this.

https://www.google.com/amp/s/engineering.careers360.com/articles/iisc-bs-eligibility-criteria/amp