Hi

After 12 std science a student can pursue Bachelor in science ( Research ) in biology, physics, maths etc. The entry level exams to get admission into following course is KVPY, IIT JEE, NEET.

Yes definetly you can apply, but you will not get admission into IISc.  IISc only picks handfull of smart students from India. To get into IISc your rank should be less than 200 i. e around 99.88 percentile.

Hello dear, 

According to your percentile in jee mains your general rank will be approx 3.5 Lakh,with this rank you cannot get admission in iisc you should have to bring a very good percentile in order to get admission in  IISC .

Hope this helps helps you