Hello aspirant, hope you are doing good.

Now, coming to your question , you can definitely get into IISC Bangalore through JEE Mains rank. Infact there are three ways through which you can get into IISC Bangalore - JEE Mains, JEE advance, KVPY, NEET. The university doesn't conduct it's own examination, so these are the only ways to get in. The cutoffs are really high as well, because the competition is very tough.

If you want to know about all the possible colleges you can get into, with your JEE Mains rank, you can get it here:

https://engineering.careers360.com/jee-main-college-predictor?icn=QnA&ici=qna_answer

Hope this helps you. Good Luck!