Hello Applicant,
I was a Bio - Maths student myself and then I got into Computer Science Engineering which is quite similar to IT so I think I am rightly experienced to answer your question.
Is it advisable? Well, no, not really. According to me, it'd be easier for you to handle the pressure in college if you get admitted to a course which is relevant with your 10 - 12th class subjects which in your case is biology.
The only time when you should consider fetting admitted to a different course is when you get a really good college or you have no other options. I went for CSE because I got a good rank in WBJEE.
To be honest, in the beginning, it was really difficult for me to be able to grasp the computer language and it took me more than a year to get familiar with them. But after that, I never faced a problem again and now I personally enjoy coding. So, if you're up for that challenge then surely you can go for IT.
Good luck dear!
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