If you want to study mathematics in UG then without Maths in 10+2 makes no sense. But it doesn't mean that for other subjects you have to need Mathematics. Like for BA courses you will need no mathematics for most of the courses. Similarly for Biology course the Chemistry and Physics are the combinations of eligibility.

So depending on your course the requirement of Maths or no math will effect. So be more specific about your question.

I hope my answer helps. All the very best for your future endeavors!