Hello Aspirant!
As per the official website of IISc Bangalore, for admission to Bachelor of Science (Research) programmes, the selection process is purely based on your merit in any one of the following exams :
1. KVPY
2. (IIT) JEE-Main
3. (IIT) JEE-Advanced
4. NEET-UG

There is no provision of interview mentioned for admission to UG courses.
However, you may need to appear for an interview if your score is below 275 marks (in JEE Mains).

For more information, you can visit :
https://www.iisc.ac.in/ug/info_brochure.html

Hope this answer will help you.

IISc Bangalore

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