IISc Bangalore only accepts JEE advanced scores with rnaks below 10000.

Jee Mains ar enot accepted unfortunately.

https://engineering.careers360.com/colleges/indian-institute-of-science-bangalore

As per your JEE Main scores you can get following :

• NIT like Assam, Arunachal pradesh, Mizoram, Nagaland, Agartala,.
  
• 
  
• IIIT Sricity, nagpur, una, Bhagalpur
  
• BIT Mesra
  
• Nirma Ahmedabad
  
• Assam University
  
• Tezpur University

Hello, 

Yes you can apply through JEE main marks as there are number of colleges who take JEE mains marks for their portal admission so you can apply through it. 

IISc Bangalore

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