Hey Tanuj:)
No worries,If you failed in class 10th and got an E grade but passed over all, it doesn't stop you from applying for B.com at DU through CUET.
CUET eligbility is based only on class 12th,not class 10th marks.So, focus on doing well in class 12th and choose your CUET subjects wisely.
For most government and private jobs,after 12th or graduation, only need you to pass class 12 and hold a degree.
So, you're fully eligible for CUET,DU B.com and most jobs.
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