Your 10+2 marks have no bearing in securing a seat in MBBS. Your NEET score and Category determine your rank in the merit list. In 2018, under State Quota, 338 marks secured a seat in Raichur Institute of Medical Science under OBC Category. That was the cut off. With 280 marks you might get a private Dental College. Having said that, cut offs change every year and are dependant on various factors like no.of seats available, no.of candidates appearing for the exam, top NEET score and difficulty of the exam. You can check the cut offs of various colleges in Karnataka at:

https://medicine.careers360.com/articles/neet-cutoff-karnataka/amp

You can also use our College Predictor services to check your options:
https://medicine.careers360.com/neet-college-predictor?utm_source=google-search&utm_medium=paid&utm_campaign=neet-clgpd

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