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Quick Facts

Medium Of Instructions	Mode Of Learning	Mode Of Delivery
English	Self Study	Video and Text Based

Course Overview

Case Studies in Personalized Medicine is an online certification course designed to help you understand how genetics is being used to refine diagnoses and personalise treatment. Biomedical advances are changing the way we treat diseases. The Case Studies in Personalized Medicine certification by Coursera will give you an overview of how genetics affects how our bodies respond to drugs, and how genetics is being used to personalise treatment for rare and common diseases. The course also discusses the ethical and operational challenges of large-scale genomic sequencing.

The Case Studies in Personalized Medicine certification consists of six modules with a total duration of 18 hours, giving you insight into the fundamentals of genetics, such as how genes work and how they are inherited. It will also explain how our genes can affect how our bodies respond to drugs, and how genetics is being used to improve the accuracy of diagnoses and to personalise treatment for individual patients. Additionally, the course will explore the ethical and operational challenges of large-scale genomic sequencing.

The Highlights

3 week course
Vanderbilt University
Subtitles in 5 languages
18 hours of learning

Programme Offerings

Certificate of completion
Online Classes
assessments
flexible schedule
Case Studies

Courses and Certificate Fees

Fees Informations	Certificate Availability	Certificate Providing Authority
INR 2414	yes	Coursera

If you opt for the certificate, the fee for the Case Studies in Personalized Medicine Certification is Rs. 2,414/-. However, you can audit the course without the certificate for free.

Case Studies in Personalized Medicine Certification Fee Structure

Particulars	Total Fee
Course with Certificate	Rs. 2,414/-
Course without Certificate	Free

Eligibility Criteria

Certification Qualifying Details

The Case Studies in Personalized Medicine certification by Coursera is offered to the ones who complete all six modules of this course successfully.

What you will learn

After completing the Case Studies in Personalized Medicine certification syllabus, you will have a better understanding of how genetic variants can contribute to human disease susceptibility. You will also learn about the ethical and operational challenges of large-scale genomic sequencing.

Upon completion of the Case Studies in Personalized Medicine training, you will learn how to choose among drug therapies based on genetic factors and understand that the functional consequences of the vast majority of genetic variants discovered by modern sequencing are still unknown.

Who it is for

GeneticistBioinformatics ScientistGeneral PhysicianDoctorBiotechnologist

The Case Studies in Personalized Medicine certification is primarily designed for physicians who are more than five years out of training. This course can also be pursued by healthcare professionals such as:

Admission Details

Candidates can check out the step-by-step process to join the Case Studies in Personalized Medicine classes:

Step 1: Browse the official URL: https://www.coursera.org/learn/personalizedmed

Step 2: Click the ‘Enroll’ button.

Step 3: Sign up or log in with your credentials.

Step 4: You will be directed to the payment gateway, there you can pay the course fee and access the modules.

Application Details

In order to enrol in the Case Studies in Personalized Medicine online course, students must sign up or log in on the official provider website.

The Syllabus

Videos

A welcome message from Dr. Roden
Introduction to Personalized Medicine
Genetics Definitions, Part I
Genetics Definitions, Part II & Types of Genetic Variants
Data Analysis, Part I: What is a Good Study?
Data Analysis, Part II: What is a Good Test?
Introduction to Drug Therapy and General Mechanisms Underlying Variability in Drug Responses
Variability in Drug Therapy
Drug Metabolism & Transport
Genetic Variability in Drug-Handling Molecules
**Inside VUMC: The Promise of Personalized Medicine

Reading

About this course

Practice Exercise

Introduction to Personalized Medicine

Discussion Prompt

What kinds of data are helpful?
What is a good study?
What is a good test?
Why might an individual who has a non-sense variant not have a phenotype?
What are causes of variability in drug action?

Videos

Family History and Inheritance Patterns
Ancestry: Genetic Variation Across Generations and Geography
Finding Disease-Associated Genes: Linkage
**Inside VUMC: From Phenotype to Genotype and Back: Studying Heart Disease in Families
Genome-Wide Association
Sequencing
**Inside VUMC: History of Sequencing Technologies

Practice Exercise

Studying Genetic Variation

Discussion Prompt

What are causes of incomplete penetrance?
How big should your GWAS sample size be?
How big would the odds ratio need to be?
Can sequencing inform understanding of common diseases?

Videos

From rare to common disease: familial hypercholesterolemia
Using Genomics to Find New Drug Targets: Familial Hypercholesterolemia
Muscle Pains During Statin Therapy (Myopathy)
HLA-Mediated Immune Reactions (Skin Rash)
Long QT Syndromes, Part 1
Long QT Syndromes, Part 2
**Inside VUMC: Studying Cardiac Arrhythmias in Cells
A Second Heart Attack a Month After a First
Headache During Venlafaxine (Antidepressant)
Respiratory Arrest After Tonsillectomy
A Bleeding Complication 5 Days After Starting Warfarin
**Inside VUMC: Genotyping
Drug Metabolism and Variable Drug Responses – Four More Examples

Practice Exercise

Case Studies, Part I

Discussion Prompt

PCSK9 mutations and familial hypercholesterolemia
Simvastatin-related myopathy
Which drug-gene interactions warrant testing?
Should RCTs be done on every pharmacogenomic association before clinical implementation?