Case Studies in Personalized Medicine
Learn about the basics of genetics and how they affect drug response with the Case Studies in Personalized Medicine certification by Coursera.
Online
3 Weeks
Free Quick Facts
| Medium Of Instructions | Mode Of Learning | Mode Of Delivery |
|---|---|---|
| English | Self Study | Video and Text Based |
Course Overview
Case Studies in Personalized Medicine is an online certification course designed to help you understand how genetics is being used to refine diagnoses and personalise treatment. Biomedical advances are changing the way we treat diseases. The Case Studies in Personalized Medicine certification by Coursera will give you an overview of how genetics affects how our bodies respond to drugs, and how genetics is being used to personalise treatment for rare and common diseases. The course also discusses the ethical and operational challenges of large-scale genomic sequencing.
The Case Studies in Personalized Medicine certification consists of six modules with a total duration of 18 hours, giving you insight into the fundamentals of genetics, such as how genes work and how they are inherited. It will also explain how our genes can affect how our bodies respond to drugs, and how genetics is being used to improve the accuracy of diagnoses and to personalise treatment for individual patients. Additionally, the course will explore the ethical and operational challenges of large-scale genomic sequencing.
The Highlights
- 3 week course
- Vanderbilt University
- Subtitles in 5 languages
- 18 hours of learning
Programme Offerings
- Certificate of completion
- Online Classes
- assessments
- flexible schedule
- Case Studies
Courses and Certificate Fees
| Fees Informations | Certificate Availability | Certificate Providing Authority |
|---|---|---|
| INR 2435 | yes | Coursera |
If you opt for the certificate, the fee for the Case Studies in Personalized Medicine Certification is Rs. 2435/-. However, you can audit the course without the certificate for free.
Case Studies in Personalized Medicine Certification Fee Structure
Particulars | Total Fee |
Course with Certificate | Rs. 2435/- |
Course without Certificate | Free |
Eligibility Criteria
Certification Qualifying Details
The Case Studies in Personalized Medicine certification by Coursera is offered to the ones who complete all six modules of this course successfully.
What you will learn
After completing the Case Studies in Personalized Medicine certification syllabus, you will have a better understanding of how genetic variants can contribute to human disease susceptibility. You will also learn about the ethical and operational challenges of large-scale genomic sequencing.
Upon completion of the Case Studies in Personalized Medicine training, you will learn how to choose among drug therapies based on genetic factors and understand that the functional consequences of the vast majority of genetic variants discovered by modern sequencing are still unknown.
Who it is for
The Case Studies in Personalized Medicine certification is primarily designed for physicians who are more than five years out of training. This course can also be pursued by healthcare professionals such as:
- General Physicians
- Doctors
- Biotechnologists
- Bioinformatics Scientists
- Geneticists
Admission Details
Candidates can check out the step-by-step process to join the Case Studies in Personalized Medicine classes:
Step 1: Browse the official URL: https://www.coursera.org/learn/personalizedmed
Step 2: Click the ‘Enroll’ button.
Step 3: Sign up or log in with your credentials.
Step 4: You will be directed to the payment gateway, there you can pay the course fee and access the modules.
Application Details
In order to enrol in the Case Studies in Personalized Medicine online course, students must sign up or log in on the official provider website.
The Syllabus
Videos
- A welcome message from Dr. Roden
- Introduction to Personalized Medicine
- Genetics Definitions, Part I
- Genetics Definitions, Part II & Types of Genetic Variants
- Data Analysis, Part I: What is a Good Study?
- Data Analysis, Part II: What is a Good Test?
- Introduction to Drug Therapy and General Mechanisms Underlying Variability in Drug Responses
- Variability in Drug Therapy
- Drug Metabolism & Transport
- Genetic Variability in Drug-Handling Molecules
- **Inside VUMC: The Promise of Personalized Medicine
Reading
- About this course
Practice Exercise
- Introduction to Personalized Medicine
Discussion Prompt
- What kinds of data are helpful?
- What is a good study?
- What is a good test?
- Why might an individual who has a non-sense variant not have a phenotype?
- What are causes of variability in drug action?
Videos
- Family History and Inheritance Patterns
- Ancestry: Genetic Variation Across Generations and Geography
- Finding Disease-Associated Genes: Linkage
- **Inside VUMC: From Phenotype to Genotype and Back: Studying Heart Disease in Families
- Genome-Wide Association
- Sequencing
- **Inside VUMC: History of Sequencing Technologies
Practice Exercise
- Studying Genetic Variation
Discussion Prompt
- What are causes of incomplete penetrance?
- How big should your GWAS sample size be?
- How big would the odds ratio need to be?
- Can sequencing inform understanding of common diseases?
Videos
- From rare to common disease: familial hypercholesterolemia
- Using Genomics to Find New Drug Targets: Familial Hypercholesterolemia
- Muscle Pains During Statin Therapy (Myopathy)
- HLA-Mediated Immune Reactions (Skin Rash)
- Long QT Syndromes, Part 1
- Long QT Syndromes, Part 2
- **Inside VUMC: Studying Cardiac Arrhythmias in Cells
- A Second Heart Attack a Month After a First
- Headache During Venlafaxine (Antidepressant)
- Respiratory Arrest After Tonsillectomy
- A Bleeding Complication 5 Days After Starting Warfarin
- **Inside VUMC: Genotyping
- Drug Metabolism and Variable Drug Responses – Four More Examples
Practice Exercise
- Case Studies, Part I
Discussion Prompt
- PCSK9 mutations and familial hypercholesterolemia
- Simvastatin-related myopathy
- Which drug-gene interactions warrant testing?
- Should RCTs be done on every pharmacogenomic association before clinical implementation?
Videos
- Cystic Fibrosis
- Marfan Syndrome
- A Case of Idiopathic Heart Failure
- Personalizing Care in Neuropsychiatric Disease
- Personalizing Care in Diabetes
- Genomics to Subtype Cancer
- A Family Member With Breast Cancer
- A Family Member With Colon Cancer
- **Inside VUMC: Organizing Infrastructure to Support Genetic Testing Decisions
Practice Exercise
- Case Studies, Part II
Discussion Prompt
- How much should a drug cost?
- What data are needed in decisions about starting lithium therapy?
- Would you order a CYP2D6 genotype before starting venlafaxine?
- When to test for BRCA1 mutations?
Videos
- Where We Are Now
- Where We Are Going
- **Inside VUMC: Using iPSCs: Drug Discovery and Drug Efficacy
- **Inside VUMC: Generating iPSCs
- Electronic Medical Records & The Learning Healthcare System (Discovery)
- Using Electronic Records to Personalize Care (Delivery)
- **Inside VUMC: Using the EMR to Ascertain Patients for Genetic Studies
- **Inside VUMC: Biobanking & DNA Extraction at BioVU
- **Inside VUMC: Personalized Medicine is a Team Sport
Practice Exercise
- Personalized Medicine in a System of Care
Discussion Prompt
- What limits our use of genomic sequencing data in practice?
- What are possible drawbacks to widespread use of EMRs?
- What are the barriers to widespread implementation of genomic medicine?
Instructors
Vanderbilt Frequently Asked Questions (FAQ's)
Yes, you can access the course materials for free by auditing the course. However, the certification is available only when you buy the course.
This online course is offered by Vanderbilt University and provided by Coursera.
Anyone interested in learning more about the role of genetics in human health can apply for this course.
This course is taught by Professor Dan Roden from Vanderbilt University.
This online course consists of six modules, spanning approximately 18 hours.