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Quick Facts

Medium Of Instructions	Mode Of Learning	Mode Of Delivery
English	Self Study	Video and Text Based

Course Overview

This course on Enzymology will enable you to analyse scientific phenomena that enzymes form a part of. This knowledge will, in turn, help you to function effectively at both the academic and professional levels. This branch of biochemistry deals with the function of enzymes and their formation into their state of origin.

As a multidisciplinary research field, Enzymology combines the fields of microbiology, biochemistry, molecular genetics, biology, and molecular biology. Hence, this subject is suitable for candidates belonging to various disciplines. The development in this subject is reflected in the advancement of the tools used by enzymologists.

And this has created an increased demand for this subject. Tasks like genomic sequencing can be conducted with gene synthesis that is available at cheap prices. And this allows enzymologists to study any enzyme and produce pure proteins without much effort.

Thorough knowledge of Enzymology can help you in building a career in biology as well as the other domains such as medical and environmental sciences. The course instructor has decades of experience in teaching this subject to the students belonging to the science department. This course will, therefore, help you in building a strong knowledge base on this subject.

The Highlights

Online mode of training
Duration of 12 weeks
Granting of a certificate post-registration
Course content prepared by a subject matter expert
Wide range of career options with the knowledge of this subject
Preparation through quizzes and tests
Certification that is recognised by the Government
Interactive classes
Access to course materials without any charges
Obtaining of Swayam certificate after completing a proctored exam

Programme Offerings

Online training
Free course materials
government certification
Self explanatory illustrations

Courses and Certificate Fees

Certificate Availability	Certificate Providing Authority
yes	Kashmir University

Eligibility Criteria

There are no prerequisites to join the course. Any student who is willing to take this undergraduate course to enhance knowledge and skills can be a part of this.

Certification Qualifying Details

The certificate is given out to students who register themselves for the proctored exam and pay the exam fee. The exam is held in-person at specific locations. Scoring a minimum of 70 percent in this exam is one of the eligibility criteria for the certificate. Another criterion is that you score at least 30 percent in the internal assessment. You will receive an e-certificate post declaration of results.

What you will learn

Knowledge of Microbiology

This course on Enzymology by Swayam will give:

Providing you with in-depth knowledge of enzymes and their mechanisms.
You will be taught on the methods of producing enzymes in large quantities, the various types of enzymes, application of soluble enzymes, protein folding, protein sequencing, as well as a qualitative description of sequential models.
Some of the other topics that this course will cover are enzyme active sites, Isozymes with their significance, transition state theories, enzyme kinetics, and protein folding.
An understanding of these along with the other topics will enable you to get familiar with the functions of enzymes.

Who it is for

Bio Medical EngineerBiochemistBioinformatics ScientistDoctorBiologist

Anybody can benefit from this course on Enzymology as the course goes beyond the field of biology. Professionals in the healthcare field as well as medical professionals can pursue this course to surge ahead in their careers.

Admission Details

Enrollment in the program can be obtained by clicking on the Join option. You will be directed to a page where you will have to fill in your details. You can then start accessing the course materials and begin the journey of knowledge.

Application Details

Application for the course can be made by creating an account on the portal. You will need to fill in your details and verify your email address by clicking on the link sent to your inbox. Once your account is created, you can click on the Join option to proceed further. All course-related details are available on the portal itself.

The Syllabus

Enzymes

Nomenclature and classification of enzymes Holoenzyme
apoenzyme
cofactors
coenzyme
prosthetic groups
metallo enzymes
monomeric and oligomeric enzymes Activation energy and transition state theory
enzyme activity
specific activity
common features of active sites
enzyme specificity: types and theories Factors affecting enzyme activity
E, S, temp and pH

Role of NAD+ NADP+
Folic acid and Vit.
B12 as biocatalysts
FMN/FAD
Coenzyme A
Lipoic acid
biotin
tetrahydrofolate and metal ions as biocatalysts
Role of thiamine pyrophosphate
pyridoxal phosphate as biocatalysts
Biocatalysts from extreme thermophillic and hyperthermophilic archea and bacteria

Enzyme substrate complex: Concept of E-S complex,
binding sites
active site
specificity
kinetics of enzyme activity
Michaelis- Menten equation and its derivation
Different plots for the determination of KM and Vmax and their physiological significance
Two substrate reactions (random, ordered and ping pong mechanisms)
enzyme inhibition
types of inhibition
determination of Ki
suicide inhibitor

Qualitative description of concerted and sequential models
Negative cooperativity
Half site reactivity
Enzyme regulation: Product inhibition,
feedback control
covalent modification

Enzyme- enzyme interaction
protein ligand binding
Measurement analysis of binding isotherm
cooperativity
Hill and Scatchard plots
Kinetics of allosteric enzymes
Allosteric enzymes with special reference to aspartate transcarbomylase and posphofructokinase

Mechanism of enzyme action
general mechanistic principle
Techniques for studying mechanism of action
Factors associated with catalytic efficiency
proximity
orientation and distortion of strain
Collision and transition state theories
significance of activation energy and free energy
Acid base
Nucleophilic and covalent catalysis

Isolation
crystallization and purification of enzymes
Test of homogeneity of enzyme preparation
methods of enzyme analysis
Detailed view of techniques for studying Enzyme assay
Chemical modification of active site groups
chymotrypsin
Lysozyme
RNase
Carboxypeptidase
GPDH
Aldolase
alcohol dehydrogenase
5 Subjective

Zymogens and their activation (proteaseses and prothrombin)
Isozymes: Multiple forms of enzymes with special reference to lactate dehydrogenase
Multienzyme complexes
Ribozymes
Multifunctional enzymes e.g., fatty acid synthase

Enzyme technology: Methods for large scale production of enzymes
immobilized enzymes and their comparison with soluble enzymes
Methods of immobilization of enzymes
immobilized enzyme reactors
Application of immobilized and soluble enzymesin health and industry
application to fundamental studies of biochemistry
enzyme electrodes
Thermal stability and catalytic efficiency of enzyme
site directed mutagenesis and enzyme engineering-selected examples
5 Subjective

Delivery system for protein pharmaceuticals,
structure function relationship in enzymes,
structural motifs and enzyme evolution
Methods of protein sequencing
Methods for analysis of secondary and tertiary structure of enzymes
Protein folding in vitro and in vivo

Evaluation process

A certificate for the course can be obtained only after you register yourself for the proctored exam against the payment of an exam fee. You need to score at least 70 percent in this exam along with 30 percent in your in-course assessment to qualify for the certificate.

Instructors

Kashmir University Frequently Asked Questions (FAQ's)

1: Why should I join the course?

Courses with Swayam are available free of cost unless the candidate wants to receive the Swayam certificate. The course is specially designed to enable students’ function in the absence of a physical structure. Hence, the course content will allow you to acquire sufficient knowledge on the subject and find a wide range of career options.

2: What materials will I be provided with?

You will be provided with online lectures delivered by an expert faculty. You will get a list of books that you can refer to. You will also have ample MCQs, self-explanatory illustrations, and short answer questions to prepare effectively on this subject.

3: Is the course valid?

Swayam courses are recognised by the Government as well as the educational institutions. The contents are designed by top-rated education providers and are accepted by the recruiting bodies as well.

4: How will the certificate help me?

Some of the universities recognise Swayam courses as credit-eligible. In such situations, the certificate can be used to earn academic credit and obtain a higher education.

5: How can I take the exam?

To take the certification exam you need to register on the portal and pay the proctored exam fee. Registration dates are announced on the portal itself. The exam is conducted in-person at designated locations.