Main reasons for RMP generation, depolarisation, repolarisation and hyperpolarisation of a normal cell?
Answer (1)
31st Mar, 2019
Reasons for Resting Membrane Potential (RMP) generation -
1. Efflux of potassium ions from ICF (intra cellular fluid) into ECF (extra cellular fluid) via K+ leaky channels
2. Na-K ATPase pump that pumps 3Na+ ions out and 2K+ ions in
Reason for depolarisation - Rapid influx of Na+ ions into the cell due to opening of Na+ voltage gated channels
Reason for repolarisation - Efflux of K+ ions into ECF from ICF via K+ ion gates
Reason for hyperpolarisation - Extra efflux of K+ ions into ECF as K+ ion gates remain open for a comparatively longer time
1. Efflux of potassium ions from ICF (intra cellular fluid) into ECF (extra cellular fluid) via K+ leaky channels
2. Na-K ATPase pump that pumps 3Na+ ions out and 2K+ ions in
Reason for depolarisation - Rapid influx of Na+ ions into the cell due to opening of Na+ voltage gated channels
Reason for repolarisation - Efflux of K+ ions into ECF from ICF via K+ ion gates
Reason for hyperpolarisation - Extra efflux of K+ ions into ECF as K+ ion gates remain open for a comparatively longer time
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