who proposed lock and key hypothesis and induced fit hypothesis?
Hello,
Lock and Key hypothesis was given by Emil Fisher . According to this hypothesis, substrates fit into active site of enzyme as key fits into lock.
Induced fit hypothesis was given by Koshland . This hypothesis states that binding of substrate with enzyme causes conformational change of enzyme that enhance its functionality.
These two hypothesis try to explain working of enzymes in biology.
Hope it helps.
All The Best!!