My neet rank is 40486 and state rank is 2227 iam bc-b in ap can I get seat in government state quota

You havent mentioned which are you a locale to and your score. Neverthless, in 2018, the cut offs for various areas for SC Category have been as follows:

AU: 441 with an AIR of 49507
SVU: 427 with an AIR of 58155
OU: 458

With your rank, you have a decent chance at a seat in a Government Medical College of AU and SVU areas. Having said that, cut offs change every year and are dependant on various factors like no.of seats available, no.of candidates appearing for the exam, top NEET score and difficulty of the exam. You can check the cut offs of various colleges in AP at:
https://medicine.careers360.com/articles/neet-cutoff-ap
You can also use our College Predictor services to check your options:
https://medicine.careers360.com/neet-college-predictor?utm_source=google-search&utm_medium=paid&utm_campaign=neet-clgpd