My sis got 501 marks and her state rank is 1600 belongs to telangana can we expect government college seat

Dear Likitha, you havent mentioned her Category. Neverthless, in 2018, under State Quota, the cut offs for various Categories have been as follows:
General Category: 474
BC: 414
SC:  393
ST: 406
Irrespective of your Category, your sister has a decent chance at a Government Medical College Seat. Having said that, cut offs change every year and are dependant on various factors like no.of seats available, no.of candidates appearing for the exam, top NEET score and difficulty of the exam. There might be a difference of give or take 25-40 marks. You can check the cut offs of various colleges in Telangana at:
https://medicine.careers360.com/articles/neet-cutoff-telangana
You can also use our College Predictor services to check your options:
https://medicine.careers360.com/neet-college-predictor?utm_source=google-search&utm_medium=paid&utm_campaign=neet-clgpd

Dear Likitha,

501 is a good score, there are chances depending upon your CAT, if you need admission guidance & assitance for counselling and application support call on 9341888827/7019595620