hi sir I got 453 marks in neet & i am from up i belong to OBC could i got this college

Hello Salil,
As you are talking about St. John's Medical College then you cannot get admission in this college with the marks you have obtained in NEET examination.
Moreover as you belong to UP and hence you will be considered in Open merit ( all India qouta) which will make your chances of admission even more difficult.
The cutoff rank for open merit this year in this college is 6490 rank for the 1st round of counseling.
With 453 score you have absolno chance of getting admission in this college.
I hope this helps.
All the best for the future!!